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Passion for scientific research and nutrition.
Endocannabinoid system and well-being.
Latest generation of natural active ingredients.
Passion for scientific research and nutrition.
Endocannabinoid system and well-being.
Latest generation of natural active ingredients.
Contact us
Research in Nutrition
Email: marketing@pharmaofficine.it
ATENAOXI 40 capsules
A multifactorial approach to combat swelling
localized and fluid accumulation.
Natural adjuvant to improve metabolic disorders.
ATENAOXI: A unique and innovative functional nutraceutical
The first one able to interact with
the endocannabinoid system
chronic inflammation
Metabolism of
macronutrients
Microcirculation
Oxidative stress
Purification
Liquid drainage
SYNERGIES OF ACTION: Act on the causes and not on the symptom
ATENAOXI is an innovative, unique nutraceutical with active natural ingredients
latest generation with synergistic action
It works by counteracting the inflammation of the soft tissues which causes fluid retention
Improves microcirculation
It has direct antioxidant action and stimulates natural antioxidant pathways to counteract cellular damage and consequent inflammation
Contributes to insulin metabolism and macronutrient metabolism
It helps to counteract the causes that lead to the accumulation of liquids
Some components of ATENAOXI are similar to the CB2R receptors of the endacannabinoid system, making it an ideal candidate for improving general well-being. Learn more about the endocannabinoid system
Fluid retention
Water retention is a multifactorial phenomenon, so the causes are multiple.
Sometimes, as soon as we wake up in the morning, we look in the mirror and see ourselves one way, and then, in the evening, we repeat the same poses and look different. After a day at work where we are always standing or sitting, and after a day of running around for our children, work and daily activities, we find ourselves feeling heavy, tired and bloated at night.
We are talking about water retention. In medicine, "retention" refers to the reduction or non-elimination of substances that our body should normally eliminate, and "hydric" means exactly water.
That is, water retention can be defined as the body's tendency to accumulate fluid in the interstitial spaces, or spaces between cells.
Among the most common symptoms of retention there is obviously a feeling of heaviness, tiredness and swelling generally localized in the lower limbs, arms, abdomen and in some cases also in the face.
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Microcirculation and swollen legs
Microcirculation is the process of blood circulating in the small arteries, veins and capillaries found in the organs and tissues of the body. It is responsible for supplying oxygen and nutrients to cells and removing metabolic waste products. When microcirculation is compromised, problems such as the sensation of swollen legs can occur. Swollen legs, also known as lower extremity edema, can be caused by several factors, including circulatory problems, trauma, venous insufficiency, excess weight, sedentary lifestyle, pregnancy or medical conditions such as heart or kidney failure. Poor microcirculation can contribute to the onset of swollen legs. If blood circulation in the small arteries, veins and capillaries is impaired, fluid retention and a build-up of waste substances in the leg tissues may occur. This can cause swelling, heaviness and discomfort.
Chronic inflammation
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In recent years, the complex phenomenon of inflammation has been extensively studied and has emerged as a key feature of metabolic disorders such as obesity, type II diabetes, non-alcoholic steatohepatitis, NAFLD.
Obesity and metabolic syndrome lead to an inflammatory state different from the classic response; The inflammatory process is systemic and is characterized by a chronic low intensity reaction. Recent studies have shown that local infiltration of immune cells leads to insulin resistance.
This is a condition caused primarily by metabolic excess.
The chronic inflammatory response develops from the interaction between adipose tissue-resident immune cells, including macrophages, and the immune system degraded towards a pro-inflammatory phenotype.
In pathological conditions such as obesity, fatty liver disease and T2D, immune cells secrete proinflammatory cytokines such as TNF-, IL- 1, IL-. 6, IL-12 and C-reactive protein.
Today, almost 30 years later, the link between obesity, diabetes and chronic inflammation has been confirmed. Hypertrophic obesity leads to disorganization of subcutaneous adipose tissue and ectopic fat accumulation in many depots, such as the liver, where inflammation and hepatocyte damage are hallmarks of NASH and NAFLD. The innate immune system also plays a critical role in triggering and amplifying hepatic inflammation in liver lipid disorders.
Oxidative stress
Oxidative stress is a term used to describe an imbalance between the production of reactive oxygen species (ROS) and the body's ability to neutralize them through antioxidant defense systems. ROS are highly reactive molecules that include free radicals such as singlet oxygen, superoxide, and hydrogen peroxide.
Normally, the body is able to manage ROS and maintain a redox balance through endogenous antioxidant enzymes, such as superoxide dismutase, catalase and glutathione peroxidase. However, stressful situations, exposure to harmful environmental agents, aging and certain pathological conditions can increase ROS production or reduce the efficiency of antioxidant mechanisms, leading to an imbalance and accumulation of ROS.
Excess ROS can damage cells and biomolecules, including DNA, proteins, and lipids, through a process called lipid peroxidation. This can lead to a wide range of negative consequences, including accelerated aging, cardiovascular disease, cancer, neurodegenerative inflammation, and other pathological conditions.
To mitigate oxidative stress, it is possible to adopt some healthy lifestyle strategies, such as a balanced diet rich in natural antioxidants (fruit, vegetables, nuts), avoid excessive exposure to environmental pollutants, regularly practice physical activity, limit the alcohol consumption and avoiding tobacco smoking. In some cases, antioxidant supplements may be prescribed, but it is important to consult with a qualified health professional about their use.
In summary, oxidative stress is a harmful biological process caused by an excess of ROS and an insufficient ability of the body to neutralize them. Reducing oxidative stress through a healthy lifestyle can help maintain overall well-being and reduce the risk of associated diseases.
The active ingredients
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The real strength of Atenaoxi is its uniqueness and innovation.
The latest generation natural active ingredients have documented scientific literature.
The synergy of action helps to counteract the accumulation of liquids, has anti-inflammatory, anti-edema and antioxidant properties.
Atenaoxi, thanks to ingredients that demonstrate activity on some cellular metabolic pathways, can perfectly integrate low-calorie food plans.
ATENAOXI goes beyond the concept of a draining supplement.
The latest generation ingredients have multi-bioactive functions
If you are a healthcare professional and would like more information about the latest-generation active ingredients, fill out the form below, and a dedicated consultant will contact you to manage access to the reserved areas.
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